$150,000
Noninvasive Clinical Monitor for Early Detection of Shock
University of Washington
Focus: To test a new instrument for the diagnosis and monitoring of shock
Shock is a life-threatening medical condition that results in insufficient oxygen reaching body tissues. Early and definitive diagnosis of shock is difficult using current methods. As a result, many cases are missed or not picked up until the critical later stages when organ failure and death may occur. The investigators have developed a novel noninvasive clinical monitor that they believe will fundamentally improve the early detection and continuous monitoring of shock. A proof-of-concept study will be performed on trauma patients upon admission to the emergency department and within the first hours of resuscitation in the intensive care unit. The investigators hope to demonstrate that their new monitor can identify the severity of shock and serve as a sensitive indicator of the adequacy of resuscitation. The commercialization plan for the shock monitor includes the formation of a new start-up company.
Grant Update
“We have successfully enrolled into our study 20 patients who have suffered traumatic injury. Preliminary analysis of data from these patients shows that their muscle oxygenation is abnormally low upon arrival in the Emergency Department, compared with health control subjects. Initial review of the values obtain shows correlation with severity of injury, with lower values noted in patients requiring more medical intervention. These preliminary results are encouraging that measurement of muscle oxygenation may be a very useful tool to help identify patients at risk for shock, and to monitor their response to treatment. ”
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